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Fig. 7 | Cell & Bioscience

Fig. 7

From: Decoding ceRNA regulatory network in the pulmonary artery of hypoxia-induced pulmonary hypertension (HPH) rat model

Fig. 7

Evaluation of the diagnostic value of potential hub mRNAs in patients with pulmonary artery hypertension (PAH). Expression profiles of LTBP2 (A), POSTN (B), SPP1 (C), and LSAMP (D) in the lung tissues of PAH patients and normal individuals. NOR: normal individuals. IPAH: idiopathic PAH; HPAH: heritable PAH, APAH: associated PAH (connective tissue disease, congenital heart defects, anorexigen/stimulant drug use, and so on). *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001. ROC curve analysis of potential diagnostic mRNAs. The AUC curve showed the effectiveness of LTBP2 (E), POSTN (F), SPP1 (G), and LSAMP (H) for the detection of the occurrence of PAH

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