Fig. 5

Potential competing endogenous RNA (ceRNA) regulatory network and protein–protein interactions (PPI) analysis in the pulmonary artery of HPH rats. A LncRNA/circRNA-miRNA-mRNA ceRNA regulatory network constructed in this study. The ceRNA regulatory network includes 10 miRNAs, 6 circRNAs, 7 lncRNAs, and 18 mRNAs. Red color indicates upregulated, green color indicates downregulated; circles indicate circRNAs, retangles indicate mRNAs, diamonds indicate lncRNAs, hexagons indicate miRNAs. B Co-expression analysis of DEmRNAs by STRING database. The squares represent gene association, more intense color of the squares represent higher association score. C Results of PPI analysis of DEmRNAs by STRING database. The balls represent the gene nodes, the connecting lines represent the interactions between genes and figures insides the balls represent protein structure