a Experimental procedures for FG pig model generation. b Schematic diagram of sgRNA-targeting exons of porcine FAH and IL2RG. c Summary of embryo transfer data from SCNT of FG knockout cell-line to generate mutant pig models. d Appearance of a 15-day-old FG model pig. e The birth weight between model and wild-type piglets. f Genomic PCR results of the FAH/ IL2RG knockout pig.