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Fig. 8 | Cell & Bioscience

Fig. 8

From: YTHDF1 promotes breast cancer progression by facilitating FOXM1 translation in an m6A-dependent manner

Fig. 8

YTHDF1 overexpression could not reverse the anti-tumor effects caused by FOXM1 knockdown in MCF-7 cells. A CCK-8 assays in shNC, shYTHDF1#2 + FOXM1-WT and sh-YTHDF1#2 + FOXM1-MUT MCF-7 cells. B Western blots for EMT-related proteins and C Transwell invasion assays in shNC, shNC + Vector, sh-YTHDF1#2 + FOXM1-MUT and sh-YTHDF1#2 + FOXM1-WT MCF-7 cells. D FOXM1 protein expression in shNC, sh-FOXM1#1 and sh-FOXM1#2 transduced cells. E Western blots for EMT-related proteins, F CCK-8 assays and G Transwell invasion assays in shNC + Vector, sh-YTHDF1#2 + FOXM1-MUT and sh-YTHDF1#2 + FOXM1-WT MCF-7 cells. All data were presented as means ± SD of at least three independent repetitions. Values are significant at *P < 0.05, **P < 0.01, ***P < 0.001 as indicated

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