Fig. 3

Comparison of iPSCs- and ESCs-derived MSCs with primary bone marrow MSCs. a Flow cytometry analyses of typical positive (CD73, CD90, CD105 and CD44) and negative (CD45, CD34, CD11b, CD19 and HDL-DR) surface markers for MSCs in WT-MSCs, H1-MSCs and BM-MSCs. b Adipogenesis, chondrogenesis and osteogenesis of WT-MSCs, H1-MSCs and BM-MSCs. Adipocyte, chondrocyte, and osteoblast are detected by the staining of Oil red O, Alizarin red S and Alcian blue, respectively. Scar bar 100 μm. c Correlation co-efficient (R2) of gene expression profiling between WT-MSCs, H1-MSCs and BM-MSCs