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Table 2 Suggested top chemicals for the Platelet changes caused by SARS-CoV-2 infection

From: Transcriptional landscape of circulating platelets from patients with COVID-19 reveals key subnetworks and regulators underlying SARS-CoV-2 infection: implications for immunothrombosis

Chemical

Dose (μM)

Cell

Score

Up

Down

References

Gabexate

10

PC3

1

0.812

 − 0.237

Yes

Phthalylsulfathiazole

10

MCF7

0.874

0.720

 − 0.198

–

Bisacodyl

11

HL60

0.868

0.694

 − 0.217

–

Boldine

12

PC3

0.858

0.567

 − 0.333

–

Valproic acid

500

HL60

0.842

0.683

 − 0.200

Yes

Estradiol

100

MCF7

0.838

0.679

 − 0.201

Yes

Ketorolac

11

MCF7

0.833

0.642

 − 0.233

Yes

Dacarbazine

22

HL60

0.829

0.754

 − 0.116

–

Pronetalol

15

MCF7

0.825

0.675

 − 0.191

Yes

GlycopyrroniumBromide

10

PC3

0.820

0.667

 − 0.193

–