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Fig. 4 | Cell & Bioscience

Fig. 4

From: Transcriptional landscape of circulating platelets from patients with COVID-19 reveals key subnetworks and regulators underlying SARS-CoV-2 infection: implications for immunothrombosis

Fig. 4

Identification and functional characterization of key subnetworks in circulating platelets during SARS-CoV-2 infection. A Global dysGCN in circulating platelets during SARS-CoV-2 infection. Network modules identified through the MFOLD are shown in distinct colors. Highly connected hub genes are labeled with respective gene symbols. B Heat map of enriched KEGG signaling pathways with FDR-adjusted P-value < 0.01 among different network modules. C Heat map of enriched GO functional terms with FDR-adjusted P-value < 0.01 among different network modules. dysGCN, dysregulated gene co-expression network; SARS-CoV-2, severe acute respiratory syndrome coronavirus 2; GO, Gene Ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes; FDR, false discovery rate

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