Fig. 5
From: Transcriptome-scale spatial gene expression in rat arcuate nucleus during puberty
Transcriptional dynamics during pubertal development. A Unsupervised pseudotime analysis showing the PND-25 (green), 35 (pinkish purple) and 45 (orange) based on their gene expression profiles. Minimal spanning tree is shown in black. B Unsupervised pseudotime analysis showing the Subcluster 1 (green), Subcluster 2 (pinkish purple), Subcluster 3 (orange) and Subcluster 4 (yellow) based on their gene expression profiles. C Unsupervised ordering of the pubertal development based on gene expression profiles of these three stages. Arrows indicate the direction of development. D Heatmap showing three groups of gene expression modules with distinct expression dynamics during pubertal development. E–G GO analysis of the genes in three modules, respectively. H Scatterplots showing the expression of Dlk1, Fto, Kiss1, Pdyn, Pou2f2 and Tac3 along the pseudo-timeline