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Table 2 Host proteins identified by iPOND-MS analysis

From: Replication and transcription machinery for ranaviruses: components, correlation, and functional architecture

Proteins

Assays for ADRV

Assays for RGV

Possible functions

1

2

3

1

2

3

Topisomerase IIα

 + 

 + 

 + 

 + 

 

 + 

DNA topological change

Topisomerase IIβ

   

 + 

 

 + 

FACT complex subunit SSRP1

 + 

 + 

 + 

  

 + 

DNA replication, DNA repair, and mRNA elongation

FACT complex subunit SPT16

 + 

 + 

 + 

  

 + 

Transcriptional repressor p66-beta

 + 

 + 

 

 + 

 + 

 

Transcriptional repressor

Histone H2A.x-like

  

 + 

 + 

 + 

 + 

DNA repair

Heterogeneous nuclear ribonucleoprotein A1

 + 

    

 + 

RNA binding/processing

ATP-dependent RNA helicase A

 

 + 

 + 

 

 + 

 

RNA helicase

ATP-dependent RNA helicase DDX3X

  

 + 

   

RNA helicase

RNA polymerase II subunit Rpb3-like

    

 + 

 + 

Transcription

DNA ligase 3

   

 + 

  

DNA repair

  1. “+” indicates the protein was detected in the corresponding iPOND assay