Skip to main content
Fig. 9 | Cell & Bioscience

Fig. 9

From: Turning the tide on Alzheimer’s disease: modulation of γ-secretase

Fig. 9

A Visualization of γ-secretase bound to E2012. PS1 is represented in orange and NCT is represented in green. Hydrogen bond between methylimidazole on E2012 and Tyr106 on PS1 is indicated by the dotted blue line. B Visualization of allosteric site and active site on γ-secretase. γ-secretase subunits represented are PS1 (green), Nicastrin (blue), PEN-2 (pink), and APH-1 (brown). Protein Data Bank entry 7D8X

Back to article page