The cGAS–STING pathway: more than fighting against viruses and cancer

Cell & Bioscience

Table 1 cGAS–STING-related autoimmune diseases

STING-related gene mutations	TREX1 mutation	DNase II mutation
VAPS	AGS	Polyarthritis
SAVI	SLE
	Familial cerebellar lupus erythematosus
	Retina with leukodystrophy Vascular disease

VAPS vascular and pulmonary syndrome, AGS Aicardi-Goutieres syndrome, DNaseII deoxyribonuclease II, SLE systemic lupus erythematosus, SAVI STING-associated vasculopathy with onset in infancy, TREX1 three prime repair exonuclease 1

ISSN: 2045-3701