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Fig. 6 | Cell & Bioscience

Fig. 6

From: Soluble amyloid-beta isoforms predict downstream Alzheimer’s disease pathology

Fig. 6

Proteome analyses results of cerebrospinal fluid (CSF) cells between true positive (TP) and false positive (FP) predictions for tau pathology positivity (T+) in cognitively unimpaired (CU) individuals. A Gene ontology (GO) network of enriched terms were constructed from differentially expressed proteins mapping the node sizes to GO term significance and edge width to shared protein proportions (Jaccard coefficient). B Radial plot of top 15 enriched GO terms. C Enriched pathways obtained from functional enrichment of KEGG terms. D–G Pie charts of enriched KEGG pathways showing the proportion of proteins upregulated in TP vs. FP comparison

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