Cell & Bioscience

Table 4 Spearman correlation coefficients of methylation levels of GAB2 and metabolic traits in mice

From: Effect of exercise and diet intervention in NAFLD and NASH via GAB2 methylation

CpG units	Liver				Adipose
CpG units	ALT	AST	Cholesterol	Triglyceride	ALT	AST	Cholesterol	Triglyceride
CpG_1.2	− 0.518	− 0.573	0.741*	0.478	− 0.091	− 0.148	− 0.154	− 0.309
CpG_3	− 0.247	− 0.577	0.083	0.255	0.177	− 0.109	− 0.156	0.086
CpG_5	0.788*	0.788*	− 0.895*	− 0.723	− 0.406	− 0.535*	0.043	0.451
CpG_6.7	0.252	0.36	− 0.318	− 0.359	0.558	0.653*	− 0.765**	− 0.645*
CpG_8	− 0.319	− 0.396	0.475	0.263	0.007	− 0.025	0.144	− 0.224
CpG_9	− 0.196	0.123	0.198	− 0.108	− 0.644*	− 0.656*	0.247	0.402
CpG_10.11.12	− 0.487	− 0.126	0.518	0.349	− 0.706**	− 0.695**	0.727**	0.681**
CpG_13.14.15	− 0.524	− 0.319	0.681	0.481	− 0.839**	− 0.830**	0.684**	0.667**
CpG_16.17	− 0.515	− 0.371	0.663	0.364	− 0.591*	− 0.629*	0.177	0.427
CpG_18.19	− 0.743*	− 0.790*	0.819*	0.920**	− 0.687**	− 0.691**	0.758**	0.552*
CpG_20.21	− 0.349	− 0.446	0.085	0.056	− 0.420	− 0.605*	0.328	0.498
CpG_23.24	− 0.476	− 0.381	0.575	0.160	− 0.066	− 0.213	− 0.389	0.183
CpG_25.26.27.28	− 0.458	− 0.386	0.752*	0.342	− 0.717**	− 0.693**	0.386	0.378
CpG_30	− 0.615	− 0.615	0.261	0.342	− 0.721**	− 0.727**	0.683**	0.463
CpG_31	0.024	0.171	− 0.160	− 0.340	− 0.773**	− 0.835**	0.609*	0.620*
CpG_33	0.091	0.378	− 0.190	− 0.686	− 0.695**	− 0.628*	0.424	0.378
AverageCpG	− 0.571	− 0.619	0.623	0.516	− 0.805**	− 0.832**	0.573*	0.491

ALT: alanine aminotransferase; AST: aspartate aminotransferase; CpG: cytosine-guanine dinucleotide; GAB2: GRB2 associated binding protein
*P < 0.05; **P < 0.01

Back to article page

ISSN: 2045-3701

Contact us

Submission enquiries: Access here and click Contact Us
General enquiries: info@biomedcentral.com