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Fig. 5 | Cell & Bioscience

Fig. 5

From: PRCC reduces the sensitivity of cancer cells to DNA damage by inhibiting JNK and ATM/ATR pathways and results in a poor prognosis in hepatocellular carcinoma

Fig. 5

High expression of PRCC made cancer cells insensitive to DNA damage. a Co-expression analysis of PRCC and molecules involved in DNA damage repair (http://www.cbioportal.org/results/coexpression). b CCK8 assay was used to detect the effect of PRCC on the UV irradiation-treated HCC cells (**, P < 0.01; ***, P < 0.001). c Flow cytometry analysis was used to analyze the cell cycle distribution after UV (5 J/m2) treatment. d CCK8 assay was used to detect the inhibition rate of DDP on HCC cells with different PRCC expression levels (*, P < 0.05; **, P < 0.01; ***, P < 0.001). e Flow cytometry analysis was used to analyze the cell cycle distribution after DDP treatment. All data were representative of three independent experiments

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