Fig. 4From: Current knowledge and challenges associated with targeted delivery of neurotrophic factors into the central nervous system: focus on available approachesCNTF signaling pathway. CNTF/CNTFR induces the MAPK and JAK/STAT pathways to inhibit cell death. JAK/STAT pathway is recruited via CNTF to induce proliferation, gliogenesis, and axonal regenerationBack to article page