Fig. 3

Propranolol pretreatment improved the T1012G mediated antitumor efficacy in a human gastric cancer xenograft model in nude mice. A Schematic plan for the administration of PBS, propranolol, T1012G, Prop + T101G, Prop → T1012G to tumor-bearing mice. B and C Tumor growth curves was plotted by average volume of six tumors for each group. D Body weight of mice were measured on day 0 and every three days thereafter. E Titers of progeny T1012G in the tumors were determined by standard plaque assays on vero cells. Results are presented as mean ± SEM. Significant differences were evaluated using one-way ANOVA. **P < 0.01 (Games-Howell’s multiple comparisons test or Dunnett’s multiple comparison test)