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Fig. 4 | Cell & Bioscience

Fig. 4

From: Loss of signal transducer and activator of transcription 3 impaired the osteogenesis of mesenchymal progenitor cells in vivo and in vitro

Fig. 4

Impairment in cancellous and cortical bone in Stat3 CKO mice of 8-week-old. A Femurs from 8-week-old control and Stat3 CKO mice. Irregular cancellous and thinner cortical bone were observed in Stat3 CKO mice. B Quantification of micro-CT data showed a significantly reduced BV/TV at trabecular bone and thinner cortical bone (nā€‰=ā€‰3, *Pā€‰<ā€‰0.05 vs Con). BMD: bone mineral density; BV/TV: bone volume/tissue volume. C. H&E-stained longitudinal sections of femurs from 8-week-old control and Stat3 CKO mice. Red arrows pointed to the cortical bone defect

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