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Fig. 3 | Cell & Bioscience

Fig. 3

From: Loss of signal transducer and activator of transcription 3 impaired the osteogenesis of mesenchymal progenitor cells in vivo and in vitro

Fig. 3

The impaired endochondral ossification was found on neonatal Stat3 CKO mice. A, B Safranin O/fast green staining of proximal ulna sections showed a decrease in the proliferative zone and an increase in the hypertrophic zone in Stat3 CKO samples when compared with the control. C, D The masson staining showed less blue-stained collagen fibers in the trabecular bone region of Stat3 CKO mice. The boxed region was enlarged in the right panel, white arrows pointing to stained collagen fibers. n = 3, *P < 0.05, **P < 0.01 vs Con

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