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Fig. 2 | Cell & Bioscience

Fig. 2

From: Loss of signal transducer and activator of transcription 3 impaired the osteogenesis of mesenchymal progenitor cells in vivo and in vitro

Fig. 2

Loss of Stat3 resulted in skeletal abnormalities. A, B Ex vivo observation of control and Stat3 CKO mice at P0 and 3w. C Alizarin red/alcian blue staining of skeletal preparations of P0 control and Stat3 CKO mice. D, E Multiple fractures were observed in Stat3 CKO mice. Compared with the littermate control, the limbs were significantly shortened. F, G Alizarin red/alcian blue from P0 samples showed dysplasia in Stat3 CKO calvaria. Compared with the littermate control, the width of sagittal suture was significantly wider in Stat3 CKO mice. Quantitative data were obtained using the ImageJ software. nā€‰=ā€‰3, *Pā€‰<ā€‰0.05 vs Con

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