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Table 2 List of potential drugs for SARS-CoV-2 infection based on the network cluster analysis

From: Inferring SARS-CoV-2 functional genomics from viral transcriptome with identification of potential antiviral drugs and therapeutic targets

Clusters

SARS-CoV-2 gene

SR gene

Drug

Interaction types

Cluster A

S, E, M, N, ORF7a

C3

Zinc chloride

Inhibitor, ligand

C3

Methyldopa

Unknown

S, E, N, ORF3a

C1R

Zinc chloride

Modulator

C1R

Methyldopa

Unknown

S, E, N, ORF3a

C1S

Zinc chloride

Modulator

C1S

Methyldopa

Unknown

S, E, M, N, ORF3a

CFB

Methyldopa

Unknown

Cluster B

S, E, M

PSMB3

Bortezomib

Inhibitor

PSMB3

Carfilzomib

Inhibitor

PSMB3

Ixazomib citrate

Inhibitor

S, E, N, ORF1ab, ORF3a

PSMC5

Carfilzomib

Inhibitor

PSMC5

Bortezomib

Inhibitor

PSMC5

Ixazomib citrate

Inhibitor

M, ORF1ab, ORF7a, ORF8

PSMC3

Carfilzomib

Inhibitor

PSMC3

Bortezomib

Inhibitor

PSMC3

Ixazomib citrate

Inhibitor