Fig. 1
Overview of SARS-CoV-2 genes and human SR genes in SARS-CoV-2 infected human cells. A Viral gene expression levels in SARS-CoV-2-infected human cells. Error bars show mean  ±  SE of results of replicates. B Differentially expressed human genes responding to virus infection. The x-axis shows all the human genes. The y-axis shows the -log10(P value) based on the paired t-test between SARS-CoV-2 infected and mock-infected cells. C Circosplot showing the SR genes of each viral gene. Circos plot’s tracks, from outer to inner, are the heatmap of log2 Fold Change between SARS-CoV-2- and mock- infected cells in GSE147507, and the P values of Spearman’s correlation test between SR genes and RT-PCR results of SARS-CoV-2 in GSE156063. D Hierarchical clustering of the pairwise correlation of SR genes (rows and columns) in GSE156063. E Heatmap showing the clustering results based on SR genes among healthy and severe COVID-19 patients in GSE171110. F Heatmap showing the expression levels of SR genes among healthy, mild, and severe COVID-19 patients in GSE164805