Fig. 5

Increased SASP factor and Bcl3 expression predicted poor prognosis in HCC patients. a Schematic of the classification of 74 HCC peritumoral tissues. b IL-8 and Bcl3 expression was detected in HCC peritumoral tissues by IHC analysis. Bar, 100 μm. c Scatterplot with fitting line showing that the expression of Bcl3 strongly correlated with IL-8 expression. Pearson’s correlation analysis provided the correlation coefficient (r) and p-value. d–f Times of OS and DFS of patients after surgery were compared in each HCC group (Kaplan–Meier method), log-rank multiple comparison tests were performed to obtain p values. g Multivariate analysis of hazard ratios for the OS time of the 32 patients. h Multivariate analysis of hazard ratios for the DFS of the 32 patients. Abbreviations: C.I., confidence interval and HR, hazard ratio