Table 2 Univariate and multivariate analysis for GC patients using the Cox regression model
From: A novel mechanism for C1GALT1 in the regulation of gastric cancer progression
Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
HR (95% CI) | P-value | HR (95% CI) | P-value | |
Gender Male vs. Female | 1.068 (0.729–1.602) | 0.831 | 1.302 (0.746–2.267) | 0.324 |
Age (years) < 60 vs. ≥ 60 | 0.725 (0.446–1.189) | 0.603 | 0.876 (0.535–1.434) | 0.775 |
Tumor size (cm) < 5 vs. ≥ 5 | 1.039 (0.534–1.713) | 0.292 | 0.914 (0.455–1.842) | 0.802 |
Differentiation Well and moderately vs. Poorly | 1.577 (1.048–1.959) | 0.304 | 1.539 (0.799–2.966) | 0.181 |
TNM stage I + II vs. III + IV | 2.533 (1.529–4.265) | 0.009* | 2.871 (1.506–5.393) | 0.063 |
Grade 1–2 vs. 3–4 | 1.352 (0.887–2.008) | 0.158 | 1.438 (0.779–2.702) | 0.261 |
Recurrence Absent vs. Present | 2.728 (1.695–4.013) | 0.025* | 2.305 (0.922–5.771) | 0.052 |
Lymph node metastasis Negative vs. Positive | 2.076 (1.243–3.022) | 0.027* | 1.356 (0.709–2.174) | 0.033* |
C1GALT1 expression Low vs. High | 1.655 (1.102–2.474) | 0.001* | 1.773 (1.094–2.565) | 0.004* |