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Table 1 The relationship between AKR1B10 expression and clinicopathological features of patients with breast cancer

From: AKR1B10 promotes breast cancer cell proliferation and migration via the PI3K/AKT/NF-κB signaling pathway

Clinical parameters

n

AKR1B10 levels (IHC)

X2

R

P

≤ 4

> 4

Age

< 50

34

23

11

1.035

0.435

0.317

≥ 50

29

16

13

LN metastasis

Yes

38

19

19

5.755

0.302

0.016

No

25

20

5

Tumor diameter (cm)

≤ 2

20

17

3

6.628

0.320

0.010

> 2

43

22

21

Ki67 (%)

≤ 20

29

22

7

4.439

0.265

0.036

> 20

34

17

17

P53 (%)

≤ 40

29

25

4

13.457

0.462

2.73E−04

> 40

34

14

20

ER

+

31

21

10

0.882

0.118

0.356

32

18

14

PR

+

25

17

8

0.653

0.102

0.427

38

22

16

ERBB2

+

45

27

18

0.242

− 0.062

0.629

18

12

6