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Table 2 Effect modification of seminal calcium and Pb of sperm quality and nested model comparisons

From: Effects of low lead exposure on sperm quality and sperm DNA methylation in adult men

  RM vs RL RH vs RL splCa (RM vs RL): splCa (RH vs RL): splCa
Rapid progressive motility
 Estimate − 10 − 0.021 − 0.2 1.2 − 0.096
 p value 0.056 0.99 0.68 0.029 0.87
 95% CI − 20 to 0.28 -11 ~ 11 − 1.2 to 0.76 0.12 to − 2.2 − 1.2 to 1.1
 p value of nested model test 0.057
Slow progressive motility
 Estimate − 2.4 − 1.9 − 0.27 0.28 0.26
 p value 0.32 0.49 0.23 0.24 0.32
 95% CI − 7.1 to 2.4 − 7.16 to 3.42 − 0.70 to 0.16 − 0.18 to − 0.74 − 0.25 to 0.77
 p value of nested model test 0.41
Non-progressive motility
 Estimate − 0.35 4 − 0.19 0.02 − 0.14
 p value 0.91 0.25 0.51 0.95 0.69
 95% CI − 6.6 to 5.9 − 2.9 to 11 − 0.76 to 0.37 − 0.59 to − 0.63 − 0.81 to 0.54
 p value of nested model test 0.9
Sperm concentration
 Estimate 8.6 21 − 2.3 − 0.28 − 2
 p value 0.58 0.22 0.11 0.86 0.25
 95% CI − 22 to 39 − 13 to 56 − 5.1 to 0.49 − 3.3 to − 2.7 − 5.3 to 1.4
 p value of nested model test 0.5
Sperm viability
 Estimate − 9.3 2.5 − 0.37 1.1 − 0.021
 p value 0.29 0.83 0.63 0.18 0.99
 95% CI − 27 to 8.2 − 20 to 25 − 1.9 to 1.1 − 0.55 to − 2.8 − 2.4 to 2.3
 p value of nested model test 0.38
Asthenozoospermia
 OR 6.2 0.27 1.1 0.83 1.1
 p value 0.05 0.22 0.2 0.055 0.34
 95% CI − 22 to 39 − 13 to 56 − 5.1 to 0.49 − 3.3 to − 2.7 − 5.3 to 1.4
 p value of nested model test 0.03