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Table 2 Cytokine and chemokine concentrations

From: Persistent deficiency of mucosa-associated invariant T (MAIT) cells during alcohol-related liver disease

Parameter HC
(n = 18–24)
Alcoholic cirrhosis
(n = 16)
Mixed cirrhosis
(n = 16–20)
Binge drinking
(n = 16–20)
TSLP (pg/ml) 5.77 ± 3.48 5.64 ± 4.89 2.11 ± 0.69** 1.79 ± 0.78**
IL-23 (pg/ml) 4.88 ± 2.49 9.47 ± 12.34* 9.62 ± 6.27* 4.27 ± 1.51
IL-12p40 (pg/ml) 50.21 ± 24.02 139.10 ± 151.39* 178.98 ± 166.71* 42.46 ± 14.87
IL-12p70 (pg/ml) 1.90 ± 0.42 2.15 ± 0.96*
IL-15 (pg/ml) 17.37 ± 23.80 59.09 ± 109.97 121.43 ± 139.51* 10.70 ± 42.48
IL-18 (pg/ml) 201.0 ± 85.4 267.37 ± 201.57 304.48 ± 177.26 283.61 ± 303.28
IL-8 (pg/ml) 3.22 ± 3.74 27.30 ± 34.52* 17.13 ± 24.24 3.28 ± 5.83
CXCL10 (pg/ml) 58.26 ± 29.22 126.24 ± 96.36* 77.40 ± 37.89 13.57 ± 9.64**
CXCL5 (pg/ml) 111.18 ± 168.80 15.74 ± 21.58* 16.45 ± 25.73* 82.79 ± 123.30
CXCL11 (pg/ml) 50.51 ± 27.56 59.16 ± 33.70* 31.58 ± 13.08 18.48 ± 6.87**
IL-7 (pg/ml) 222.01 ± 46.40 247.52 ± 43.39 119.58 ± 21.01** 175.22 ± 42.59*
IL-26 (pg/ml) 324.42 ± 122.10 240.47 ± 115.20 609.6 ± 177.29** 485.3 ± 160.26**
CCL11 (pg/ml) 50.51 ± 27.56 59.16 ± 33.70 31.58 ± 13.08 18.48 ± 6.87*
CCL2 (pg/ml) 294.88 ± 245.48 260.48 ± 169.80 152.33 ± 71.46* 99.41 ± 109.09*
CXCL9 (pg/ml) 26.89 ± 30 42.51 ± 55.05 29.70 ± 29.51 6.14 ± 9.83*
  1. All values presented as the mean ± SEM. p-values were determined by the one-way analysis of variance (ANOVA) least significant difference (LSD), or Welch’s ANOVA test (Games–Howell test)
  2. HC healthy controls, TSLP thymic stromal lymphopoietin, IL, interleukin, CXCL chemokine (C–X–C motif) ligand, CCL chemokine (C–C motif) ligand
  3. *p < 0.05, **p < 0.01, (compared with blood samples from healthy controls)