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Fig. 1 | Cell & Bioscience

Fig. 1

From: Current insights into the implications of m6A RNA methylation and autophagy interaction in human diseases

Fig. 1

The process of macro-autophagy and its epigenetic regulation. A Autophagy is initiated with the formation of ULK1 complex (ULK1-ATG13-FIP200). BECN1, ATG14 and PI3K complex facilitate the formation of phagophore. ATG5-ATG12-ATG16 complex and PE-conjugated-LC3II promote phagophore elongation and autophagosome formation. Autophagosome fusion with the lysosome results in the degradation of target molecules. B Epigenomic modifications in DNA, RNA, and histones regulate autophagy by modifying the expression of autophagy-related genes or affecting the autophagy-associated signaling pathways

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Cell & Bioscience

ISSN: 2045-3701

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