Table 1 This table shows the 100 most dysregulated genes with a p value of < p = 0.005
Gene symbol | INS Avg (log2) | SST Avg (log2) | INS Standard deviation | SST Standard deviation | Fold change | p-val |
|---|---|---|---|---|---|---|
RNU7-26P | 6.85 | 4.43 | 1.83 | 0.21 | − 5.33 | 0.00110 |
RNU7-53P | 8.17 | 6.02 | 1.98 | 0.75 | − 4.45 | 0.00270 |
MIR3198-1 | 8.15 | 6.1 | 1.34 | 0.67 | − 4.15 | 0.00400 |
MTND4LP1 | 8.84 | 7.01 | 0.93 | 0.4 | − 3.56 | 0.00010 |
MIR548T | 5.87 | 4.04 | 1.22 | 0.21 | − 3.55 | 0.00040 |
MIR181A1 | 3.75 | 5.4 | 0.43 | 0.83 | 3.16 | 0.00100 |
SNORA41 | 9.39 | 7.76 | 0.94 | 0.26 | − 3.1 | 0.00040 |
LINC01628 | 4.49 | 6.08 | 0.45 | 0.73 | 3.02 | 0.00040 |
SNRPGP11 | 7.47 | 5.92 | 0.76 | 0.58 | − 2.93 | 0.00070 |
RNU6-866P | 8.7 | 7.17 | 0.45 | 0.58 | − 2.9 | 0.00010 |
MED6P1 | 5.76 | 4.26 | 0.8 | 0.34 | − 2.83 | 0.00470 |
HNRNPD | 5.45 | 4.01 | 0.46 | 0.46 | − 2.7 | 0.00050 |
RNU2-36P | 5.93 | 4.5 | 0.48 | 0.47 | − 2.69 | 0.00007 |
SNORA46 | 6.99 | 5.58 | 1.14 | 0.22 | − 2.65 | 0.00200 |
MIR373 | 7.24 | 5.88 | 0.33 | 0.23 | − 2.57 | 0.00002 |
RNA5-8SP3 | 5.41 | 4.09 | 0.57 | 0.43 | − 2.51 | 0.00170 |
RNU7-24P | 6.27 | 4.94 | 0.85 | 0.36 | − 2.51 | 0.00180 |
MIR1277 | 6.21 | 4.88 | 0.54 | 0.83 | − 2.5 | 0.00100 |
YWHAZP5 | 6.06 | 4.75 | 0.63 | 0.42 | − 2.49 | 0.00040 |
MIR548AC | 12.26 | 10.97 | 1.3 | 0.52 | − 2.45 | 0.00270 |
GPN1 | 3.77 | 5 | 0.32 | 0.61 | 2.35 | 0.00200 |
MIR548F5 | 7.01 | 5.81 | 0.71 | 0.6 | − 2.31 | 0.00280 |
PHF12 | 8.04 | 6.84 | 0.62 | 0.58 | − 2.29 | 0.00180 |
RNY4P37 | 5.13 | 3.94 | 0.62 | 0.2 | − 2.28 | 0.00007 |
RAB11AP1 | 4.04 | 5.18 | 0.46 | 0.79 | 2.2 | 0.00270 |
C1orf123 | 6.23 | 5.1 | 0.74 | 0.68 | − 2.18 | 0.00220 |
RN7SL748P | 5.53 | 4.42 | 0.71 | 0.57 | − 2.15 | 0.00360 |
ZNF965P | 5.81 | 4.71 | 0.38 | 0.44 | − 2.13 | 0.00470 |
MTND1P23 | 18.75 | 17.67 | 0.85 | 0.81 | − 2.12 | 0.00230 |
RN7SKP146 | 6.26 | 5.18 | 0.63 | 0.4 | − 2.12 | 0.00400 |
RNU7-188P | 5.43 | 4.35 | 0.76 | 0.32 | − 2.11 | 0.00250 |
MTND3P3 | 5.9 | 4.82 | 0.45 | 0.42 | − 2.11 | 0.00260 |
POLR3KP1 | 4.08 | 5.15 | 0.24 | 0.31 | 2.09 | 0.00007 |
RNU6-250P | 3.82 | 4.89 | 0.24 | 0.51 | 2.09 | 0.00110 |
ZNF248 | 5.68 | 4.63 | 0.23 | 0.43 | − 2.08 | 0.00040 |
SENP7 | 4.92 | 3.89 | 0.58 | 0.17 | − 2.05 | 0.00040 |
MIR5684 | 8.43 | 7.4 | 0.65 | 0.67 | − 2.04 | 0.00270 |
RNU1-133P | 5.7 | 4.68 | 0.7 | 0.46 | 2.04 | 0.00360 |
MIR5003 | 6.02 | 4.99 | 1.15 | 0.44 | 2.04 | 0.00430 |
GXYLT1P5 | 4.3 | 5.32 | 0.43 | 0.62 | 2.03 | 0.00230 |
RNU6-882P | 3.95 | 4.95 | 0.28 | 0.36 | 2.01 | 0.00180 |
DNAJC11 | 4.75 | 3.76 | 0.68 | 0.25 | − 2 | 0.00100 |
RNU6-571P | 5.97 | 4.96 | 0.45 | 0.3 | − 2 | 0.00120 |
RPS12P2 | 6.08 | 5.08 | 0.45 | 0.59 | 2 | 0.00290 |
MALT1 | 3.79 | 4.78 | 0.21 | 0.76 | 2 | 0.00330 |
RNY4P34 | 7.19 | 6.2 | 0.43 | 0.46 | − 1.99 | 0.00070 |
RNU7-41P | 4.97 | 3.99 | 0.45 | 0.19 | − 1.97 | 0.00050 |
SCARNA11 | 6.47 | 5.5 | 0.5 | 0.38 | 1.97 | 0.00160 |
GAPDHP28 | 4.7 | 3.72 | 0.68 | 0.11 | 1.97 | 0.00190 |
FTH1P7 | 7.46 | 6.48 | 0.3 | 0.53 | 1.97 | 0.00210 |
MEOX2-AS1 | 4.41 | 5.38 | 0.27 | 0.77 | 1.96 | 0.00250 |
U7 | 4.21 | 5.17 | 0.41 | 0.41 | 1.95 | 0.00270 |
RNU1-32P | 6.47 | 5.52 | 0.78 | 0.25 | − 1.94 | 0.00320 |
RNU6-966P | 5.49 | 4.54 | 0.6 | 0.26 | − 1.94 | 0.00400 |
LAPTM4BP2 | 4.02 | 4.97 | 0.29 | 0.56 | 1.94 | 0.00130 |
CSHL1 | 4.01 | 4.96 | 0.19 | 0.65 | 1.94 | 0.00470 |
ZBTB20-AS4 | 4.1 | 5.05 | 0.3 | 0.47 | 1.93 | 0.00180 |
OMG | 4.25 | 5.19 | 0.42 | 0.4 | 1.92 | 0.00140 |
IGLV3-15 | 6.04 | 5.1 | 0.46 | 0.16 | − 1.91 | 0.00360 |
MTCO1P3 | 5.71 | 4.77 | 0.38 | 0.42 | − 1.91 | 0.00410 |
CA5BP1 | 6.98 | 6.06 | 0.48 | 0.28 | − 1.9 | 0.00100 |
UQCRHP4 | 4.75 | 3.83 | 0.34 | 0.22 | − 1.89 | 0.00040 |
MTCO3P12 | 15.24 | 14.32 | 0.76 | 1.12 | − 1.89 | 0.00170 |
MTND6P11 | 8.08 | 7.16 | 0.55 | 0.85 | − 1.89 | 0.00170 |
FAR1P1 | 5.21 | 4.29 | 0.42 | 0.35 | − 1.89 | 0.00230 |
RPL30P15 | 3.93 | 4.85 | 0.36 | 0.46 | 1.89 | 0.00430 |
ATXN1 | 7.17 | 6.26 | 0.23 | 0.45 | − 1.88 | 0.00060 |
MIR450A1 | 4.47 | 5.38 | 0.43 | 0.28 | 1.88 | 0.00100 |
HMGN2P31 | 6.09 | 5.18 | 0.23 | 0.26 | − 1.87 | 0.00010 |
HMGN2P31 | 6.09 | 5.18 | 0.23 | 0.26 | − 1.87 | 0.00010 |
RPL21P32 | 4.99 | 4.09 | 0.37 | 0.31 | − 1.87 | 0.00270 |
RN7SKP94 | 7.73 | 6.84 | 0.41 | 0.37 | − 1.86 | 0.00100 |
MIR543 | 4.89 | 4.07 | 0.5 | 0.38 | − 1.76 | 0.00140 |
HMGN2P15 | 6.99 | 6.1 | 0.61 | 0.18 | − 1.85 | 0.00140 |
HNRNPH3 | 5.73 | 4.84 | 0.38 | 0.34 | − 1.85 | 0.00180 |
TCTA | 7.11 | 6.23 | 0.59 | 0.44 | − 1.85 | 0.00440 |
IKZF3 | 4.87 | 3.99 | 0.47 | 0.13 | − 1.84 | 0.00080 |
SUMO2P15 | 5.17 | 4.29 | 0.41 | 0.46 | − 1.84 | 0.00300 |
UBDP1 | 5.17 | 4.3 | 0.45 | 0.39 | − 1.83 | 0.00360 |
FAM81B | 3.89 | 4.76 | 0.33 | 0.27 | 1.83 | 0.00050 |
DHX9 | 4.09 | 4.97 | 0.34 | 0.55 | 1.83 | 0.00350 |
HERC2P8 | 5.21 | 4.35 | 0.42 | 0.15 | − 1.82 | 0.00020 |
RNU6-139P | 5.24 | 4.38 | 0.49 | 0.37 | − 1.82 | 0.00070 |
ULK4P3 | 6.46 | 5.6 | 0.34 | 0.38 | − 1.82 | 0.00150 |
MIR450B | 4.95 | 4.08 | 0.42 | 0.27 | − 1.82 | 0.00220 |
C3orf35 | 4.92 | 4.06 | 0.5 | 0.21 | − 1.82 | 0.00480 |
OTUD3 | 5.15 | 4.3 | 0.48 | 0.25 | − 1.81 | 0.00200 |
RPL36AP48 | 3.94 | 4.8 | 0.16 | 0.41 | 1.81 | 0.00190 |
FAM157C | 4.96 | 4.12 | 0.42 | 0.25 | − 1.8 | 0.00120 |
MTCO1P5 | 5.1 | 4.26 | 0.3 | 0.2 | − 1.79 | 0.00220 |
FAM177B | 4.69 | 3.85 | 0.59 | 0.18 | − 1.79 | 0.00250 |
RNU6-903P | 4.04 | 4.88 | 0.4 | 0.35 | 1.79 | 0.00190 |
HMGN1P24 | 5.06 | 4.23 | 0.36 | 0.15 | − 1.78 | 0.00060 |
TARDBPP1 | 5.55 | 4.72 | 0.68 | 0.15 | − 1.78 | 0.00200 |
DCDC5 | 4.42 | 3.59 | 0.51 | 0.28 | − 1.78 | 0.00490 |
MTCO3P22 | 5.56 | 4.73 | 0.47 | 0.27 | − 1.77 | 0.00340 |
LINC00243 | 4.51 | 3.69 | 0.32 | 0.34 | − 1.76 | 0.00330 |
PRKG2 | 5.17 | 4.36 | 0.56 | 0.29 | − 1.76 | 0.00460 |
COX6CP17 | 6.36 | 5.56 | 0.4 | 0.24 | − 1.75 | 0.00300 |
RN7SKP177 | 6.8 | 6 | 0.35 | 0.22 | − 1.74 | 0.00030 |