Fig. 4

DMD-delE51 pigs exhibited symptoms of malnutrition. A Photograph of DMD-delE51 pigs and WT control at the age of 1 week. B Body mass of DMD-delE51 and WT pigs from birth to 12 weeks of age. C, D Serum ALB and PA levels of WT and DMD-delE51 pigs. E, F The contents of glycogen and triglyceride in diaphragm and gastrocnemius muscle. G H&E staining of the small intestine sections of WT and DMD-delE51 pigs. Red dotted lines indicate the thickness of the intestinal wall, black arrows indicate the height of the small intestine villi and blue arrows indicate the depth of the small intestine crypt. H The thickness of small intestinal wall in WT and DMD-delE51 pigs. I The relative ratio of small intestine villus height/crypt depth of WT and DMD-delE51 pigs. Scale bars: 50 µm and 100 µm. ***P < 0.001, **P < 0.01 and *P < 0.05; n = 5