Fig. 5

A Thioflavin staining of βA plaques (Green). Images were obtained from cortex. Scale bar 50 µm. B Representative histogram of the quantification of Aβ deposits (n = 4–6 independent samples per group, with at least 5 slices analyzed per simple). Two-way ANOVA statistical test was performed (Treatment variable: ### denote p < 0.001) (Diet variable: #### denote p < 0.0001). C, D Immunoblot representative images and GAPDH-normalized quantifications of molecules related to non-amyloidogenic pathway (pro-ADAM10 and ADAM10) from hippocampal extracts (n = 4–6 independent samples per group). Statistical analysis was performed through two-way ANOVA. (Pro-ADAM10, treatment and diet variables: ### denote p < 0.001). (ADAM10, treatment variable: ####denote p < 0.0001 and diet variable: ## denote p < 0.01)