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Fig. 7 | Cell & Bioscience

Fig. 7

From: ADP/ATP translocase 1 protects against an α-synuclein-associated neuronal cell damage in Parkinson’s disease model

Fig. 7

Hypothetical conclusive mechanism of neurodegenerative disorder associated with ANT1. The pathway was summarized according to the pathway shown in KEGG website (https://www.kegg.jp/kegg-bin/highlight_pathway?scale=1.0&map=hsa05012&keyword=MPTP). Comp, complex; VMAT, vesicular monoamine transporter; DAT, dopamine transporter; TH, tyrosine hydroxylase; mPTP is composed of ANT1, cytosolic benzodiazepine receptor, Bax, and CypD. Red arrows displayed the detected changes occurred in impaired neuronal cells in this study. “ + ” indicated the promoted processes, “−” indicated the inhibited processes

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