Fig. 8From: Metabolomic and transcriptomic profiling of adult mice and larval zebrafish leptin mutants reveal a common pattern of changes in metabolites and signaling pathwaysGenes involved in arachidonic acid pathway in human orthologs of the three transcriptome signature sets. Dashed lines means indirect regulation. Red color represents genes significantly changed in ob/ob mice head compared to control. Blue color represents genes significantly changed in ob/ob mice liver compared to wild type published by Kokaji et al. Green color represents genes significantly changed in lepb mutant zebrafish larvae compared to wild type siblings. COX cyclo-oxygenase, LOX lipoxygenase, EOX epoxygenase, DHA docosahexaenoic acidBack to article page