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Fig. 8 | Cell & Bioscience

Fig. 8

From: Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma

Fig. 8

Inhibition of tumor growth in vivo by the combination of apatinib and CQ with paclitaxel. a Representative images of xenograft tumors were shown. b Tumor volume was assessed weekly. c Tumor weight was calculated for each group. d Representative IHC staining images of Cleaved-Caspase3, Ki67 were shown of every group and TUNEL assay was used for measuring apoptosis. e–g Quantitative analysis of IHC staining and TUNEL assay results. * p < 0.05, ** p < 0.01, *** p < 0.001 compared with control group

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Cell & Bioscience

ISSN: 2045-3701

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