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Fig. 2 | Cell & Bioscience

Fig. 2

From: Apatinib induces endoplasmic reticulum stress-mediated apoptosis and autophagy and potentiates cell sensitivity to paclitaxel via the IRE-1α–AKT–mTOR pathway in esophageal squamous cell carcinoma

Fig. 2

Apatinib induced cell cycle arrest and the apoptosis of ESCC cells. ac Cell cycle phase distribution was measured by flow cytometry. df Annexin V-FITC and propidium iodide (PI) staining were used to measure apoptotic ESCC cells treated with apatinib for 24 h. gi Western blot analysis was performed to measure the expression levels of apoptosis markers after cells were incubated with apatinib for 24 h. * p < 0.05, ** p < 0.01, *** p < 0.001 compared with control group

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