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Fig. 4 | Cell & Bioscience

Fig. 4

From: CD44 fucosylation on bone marrow-derived mesenchymal stem cells enhances homing and promotes enteric nervous system remodeling in diabetic mice

Fig. 4

Transplantation of FTVII-modified BMSCs restored the spontaneous contraction of the colon in diabetic mice. A The representative schematic diagram of the spontaneous contraction of the colon strips. B The contractility (included amplitude, frequency and muscle tension, analyzed as grams for 1 min) of each group. C The representative schematic diagram of colon contraction response induced by EFS at the frequency of stimulation (64 Hz) in each group. D Quantification of colon strip in response to EFS in each group. FTVII: fucosyltransferase VII; Control: the control C57 mice; DM: diabetic mice; DM + BMSCs: diabetic mice injected with unmodified BMSCs; DM + F-BMSCs: diabetic mice injected with FTVII-modified BMSCs; EFS: electrical field stimulation. Results were expressed as mean ± SD, *P < 0.05, **P < 0.01, NS no significance, n = 6

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