Fig. 7
PRMT1 knockout increases cell death in the intestine. The proximal and distal small intestine of 8-week-old adult wild type (PRMT1fl/flVil-Cre−/−) or intestinal epithelium-specific PRMT1 knockout (PRMT1fl/flVil-Cre+/−) mice were sectioned and analyzed with TUNEL for apoptotic cells (red) and DAPI for DNA (blue) (A). The apoptotic cells per villus-crypt unit were quantified from multiple sections per animal (B). For both PRMT1 knockout and control wild type littermates, n = 4. *p < 0.05, **p < 0.01