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Fig. 3 | Cell & Bioscience

Fig. 3

From: Protein arginine methyltransferase 1 regulates cell proliferation and differentiation in adult mouse adult intestine

Fig. 3

PRMT1 knockout does not affect intestinal stem cell number. The proximal small intestine of 13-week-old adult wild type (PRMT1fl/flVil-Cre−/−) or intestinal epithelium-specific PRMT1 knockout (PRMT1fl/flVil-Cre+/−) mice were sectioned and analyzed by in situ hybridization with Olfm4 probe for crypt base stem cells (A). The number of stem cells were counted visually from multiple sections per animal (B). For both PRMT1 knockout and wild type littermates, n = 4. *p < 0.05, **p < 0.01

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