Fig. 5

Energy metabolism analysis in both the JAZF1-Het and the JAZF1-Cont mice. The JAZF1-Het (Het) and the control (Cont) mice were fed with ND for 8 weeks starting at 8-week-old. After 8 weeks of ND feeding, a The average oxygen consumption and b volume of carbon dioxide production (VCO₂) production were measured in both the JAZF1-Het and the JAZF1-Cont mice (n = 6). c Energy expenditure (EE, left panel) in JAZF1-Het and JAZF1-Cont mice fed with ND for 8 weeks (n = 6). The bar graph (right panel) represents average EE values also calculated during the day and night. d Respiratory exchange ratio (RER; VCO₂/VO₂, left panel) in JAZF1-Het and JAZF1-Cont mice fed with ND for 8 weeks (n = 6). The bar graph represents average RER values (right panel) also calculated during the day and night. All data were collected by indirect calorimetry for 24 h (7 AM to 7 PM). All data are shown as mean ± SEM