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Fig. 7 | Cell & Bioscience

Fig. 7

From: Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway

Fig. 7

Increased Lrp4 mRNA expression by Wnt ligands. C2C12 myoblasts were transfected with plasmids. The resulting myotubes were subjected to qRT-PCR. a Lrp4 mRNA increased by Wnt3, wnt3a, wnt5a, wnt9a, and wnt10a. b Effects of Wnt ligands on MuSK, Dok7, rapsyn, and AChRγ- and ε-subunits. c No effect of agrin or MuSK or its mutant on LRP4 expression. **p = 0.0038 ***p = 0.001, ****p < 0.0001, n ≥ 4, one-way ANOVA

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