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Fig. 3 | Cell & Bioscience

Fig. 3

From: Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway

Fig. 3

Requirement of LRP4 for Lrp4 β-gal at NMJ in neonatal mice. Diaphragms were isolated from P0 mice of indicated genotypes. a Representative images. Colocalizing β-gal with AChR in lacZ/+, but not lacZ/lacZ mice. Synaptic β-gal staining was restored in lacZ/lacZ mice by HSA-Lrp4tg. b–e Quantitative analysis of β-gal bandwidth (b), the bandwidth of AChR (c), AChR cluster density (d), and mRAN of lacZ and Lrp4 (e). a–e ****p < 0.0001. n = 7–10 mice per group, one-way ANOVA. e n = 3 mice per group

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