Fig. 2From: Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathwayRequirement of Lrp4/MuSK signaling for central region localization of Lrp4 β-gal in mouse embryos. Diaphragms were isolated from E14 embryos of indicated genotypes. a Representative images. The increased bandwidth of Lrp4 β-gal in lacZ/lacZ and MuSK-kd;lacZ/+ mice. b Quantitative analysis of Lrp4 β-gal bandwidth. c The mRNA levels of lacZ and Lrp4 in lacZ/lacZ and MuSK-kd;lacZ/+ mice. The transcription activity of the Lrp4 promoter didn’t require Lrp4 and MuSK in vivo. Data were shown as mean ± SEM, ****p < 0.0001, n ≥ 6 per group, one-way ANOVABack to article page