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Fig. 2 | Cell & Bioscience

Fig. 2

From: Subcellular localization of the mouse PRAMEL1 and PRAMEX1 reveals multifaceted roles in the nucleus and cytoplasm of germ cells during spermatogenesis

Fig. 2

Localization of PRAMEL1 in the nucleus and nuclear envelop of spermatogenic cells. Large clusters of PRAMEL1 gold particle (red arrows) were detected in the nucleus (N) of all types of spermatogenic cells. Low density of clusters was seen in the nucleus of spermatogonia (A) and higher density of clusters were seen in spermatids (step 7) (B). No PRAMEL1 labeling was seen in the nucleolus (No) of spermatogonia (A). Heavy labeling of PRAMEL1 gold particles was detected in the nuclear envelop (NE) or nuclear pore (NP) region in steps 6–7 spermatids (C, D). AV: acrosome vesicle; CB: chromatoid body; M: mitochondria; Man: Manchette. Scale bar = 2 μm in A and B, or 0.5 μm (or 2 μm in the insert images) in C, D

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