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Fig. 1 | Cell & Bioscience

Fig. 1

From: CpG oligodeoxynucleotides attenuate RORγt-mediated Th17 response by restoring histone deacetylase-2 in cigarette smoke-exposure asthma

Fig. 1

CpG-ODN and BUD alleviate airway inflammation in the lung tissue in mice after OVA-challenge and CS-exposure. Lung tissue samples were histologically assessed 48 h upon final OVA exposure. Representative micrographs of ECP stained specimens (×200) (a). Representative micrographs of Gr-1 stained samples (×200) (b). Eotaxin 1 in BALF was assessed by ELISA (c). ECP-positivity rate was assessed as Gr-1-positive area/total bronchiole area (d). Gr-1-positivity rate was derived as Gr-1-positive area/total bronchiole area (e). Statistical significance denoted:*, #p < 0.05, **,##p < 0.01. *versus the vehicle control group; # versus the indicated group

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