Fig. 7

RRM2 silencing suppresses LUAD cells growth in nude mice model. Nude mice were injected with LV-NC and LV-siRRM2 infected A549 cells. a The tumor volumes were measured every 3 days and depicted in the line chart. b On the 40th day of injection, the tumors were collected for photograph. c The final weights of tumors were recorded. d Representative Ki-67 staining of tumor tissues. Scale bar: 100 μm. e Representative H&E staining and IHC (RRM2 and STING) of tumor tissues. Scale bar: 100 μm. *p < 0.05, **p < 0.01