Fig. 4

Disruption of EIF5A2 expression led to the inhibition of cell migration and invasion in ovarian cancer cells. a Cell migration in EIF5A2 KO and control SKOV3 or OVCAR8 cells was examined using the Transwell plates, and migrated cells were stained with crystal blue and counted from at least three different fields. b Cell invasion in both EIF5A2 KO and control SKOV3 or OVCAR8 cells was examined using Matrigel-coated plates, and invaded cells were stained with H&E. and counted from at least three different fields c Cell migration in EIF5A2-expressing and control OVCAR3 cells was examined using transwell plates, and migrated cells were stained with crystal blue and counted from at least three different fields. d Cell invasion in EIF5A2-expressing OVCAR3 and control was examined using Matrigel-coated plates, and invaded cells were stained with H&E. and counted from at least three different fields (**P < 0.01; ***P < 0.001)