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Fig. 1 | Cell & Bioscience

Fig. 1

From: EIF5A2 controls ovarian tumor growth and metastasis by promoting epithelial to mesenchymal transition via the TGFβ pathway

Fig. 1

EIF5A2 expression is upregulated or amplified in ovarian cancer and associated with patient poor survival. a EIF5A2 copy numbers in normal and cancer tissues. 1: normal ovaries (N = 130); 2: normal blood (n = 431). 3: OC (n = 607). b EIF5A2 is amplified in majority of cancer types from in TCGA database. c EIF5A2 copy number is correlated with EIF5A2 mRNA expression from RNA-seq in two different datasets including TCGA PanCan and firehose legacy. d Protein expression of EIF5A2 in normal and ovarian cancer tissues. Normal ovaries (N = 25), Ovarian cancer (N = 100). e EIF5A2 expression is associated with overall survival of ovarian cancer patients in Kaplan Meier Plotter database f Ovarian cancer patients displayed significantly reduced patient survival in the high-risk compared to the low-risk group

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Cell & Bioscience

ISSN: 2045-3701

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