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Fig. 6 | Cell & Bioscience

Fig. 6

From: Glioblastoma stem cell (GSC)-derived PD-L1-containing exosomes activates AMPK/ULK1 pathway mediated autophagy to increase temozolomide-resistance in glioblastoma

Fig. 6

Inhibition of AMPK/ULK1 pathway abrogated the inhibiting effects of PD-L1-ex on TMZ-induced cell apoptosis in TS-GBM cells in vitro. a–d By conducting Annexin V-FITC/PI double staining assay, the apoptosis ratio was examined in the TS-GBM cells co-treated with TMZ, PD-L1-ex, SBI-0206965 and compound C. (Note: “Con” indicated “Control”, “T” suggested “TMZ”, “P” represented “PD-L1-ex”, “S” suggested “SBI-0206965”, and “C” represented “compound C”). Each experiment had at least 3 repetitions, and *P < 0.05

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Cell & Bioscience

ISSN: 2045-3701

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