Skip to main content
Fig. 4 | Cell & Bioscience

Fig. 4

From: Glioblastoma stem cell (GSC)-derived PD-L1-containing exosomes activates AMPK/ULK1 pathway mediated autophagy to increase temozolomide-resistance in glioblastoma

Fig. 4

Targeting PD-L1 affected TMZ-resistance in both TS-GBM and TR-GBM cells. By performing the Annexin V-FITC/PI double staining assay, cell apoptosis ratio was determined. a PD-L1 was upregulated in TS-GBM cells, and the results indicated that PD-L1 overexpression increased TMZ-resistance in TS-GBM cells. b Knock-down of PD-L1 enhanced TMZ-sensitivity in TR-GBM cells. Each experiment had at least 3 repetitions, and *P < 0.05

Back to article page

Cell & Bioscience

ISSN: 2045-3701

Contact us