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Fig. 3 | Cell & Bioscience

Fig. 3

From: Glioblastoma stem cell (GSC)-derived PD-L1-containing exosomes activates AMPK/ULK1 pathway mediated autophagy to increase temozolomide-resistance in glioblastoma

Fig. 3

Blockage of autophagy by 3-MA abrogated the promoting effects of PD-L1-ex on TMZ-resistance in TS-GBM cells. The TS-GBM cells were co-treated with TMZ, PD-L1-ex and 3-MA. a-c Cell proliferation was determined by CCK-8 assay. d Annexin V-FITC/PI double staining assay was performed to measure cell apoptosis. Each experiment had at least 3 repetitions, and *P < 0.05

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Cell & Bioscience

ISSN: 2045-3701

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