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Fig. 4 | Cell & Bioscience

Fig. 4

From: Involvement of HECTD1 in LPS-induced astrocyte activation via σ-1R-JNK/p38-FOXJ2 axis

Fig. 4

Upregulation of σ-1R and activation of JNK/p38 and Akt pathway in LPS-induced astrocyte activation. a Treatment of astrocytes with 100 ng/ml LPS significantly increased the expression of σ-1R. Representative immunoblots and the densitometric analysis from three separate experiments are presented. b-e Western blot analysis of time-dependent activation of JNK (b), p38 (c), ERK (d) and Akt (e) by LPS (100 ng/ml) in primary mouse astrocytes. All the data are presented as mean ± SEM of three individual experiments. *p < 0.05, **p < 0.01, and ***p < 0.001 vs. the control group

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